microsatelliteinstability

由 LA Gian 著作 · 2018 · 被引用 178 次 — MSI occurs in around 15% of all CRC tumors in white populations (18-19). It arises as a result of defective MMR caused by the failure of one of the four main ...

Microsatellites are short, repeated sequences of DNA. Microsatellite instability-high cancer cells may have a defect in the ability to correct mistakes that ...

A change that occurs in certain cells (such as cancer cells) in which the number of repeated DNA bases in a microsatellite (a short, repeated sequence of ...

2023年3月6日 — Specific genes monitor the DNA for mistakes and then repair them. This built-in ability to error-correct is called mismatch repair, and the ...

2019年6月18日 — 微星體不穩定性(microsatellite instability，MSI)是大腸癌發生的重要分子機制之一，約佔sporadic大腸直腸癌之15%，對大腸直腸癌具有重要臨床意義。MSI ...

由 K Li 著作 · 2020 · 被引用 348 次 — The instability of one site is called low microsatellite instability (MSI-L), and the instability of two or more sites is called high ...

Microsatellite instability (MSI) is the condition of genetic hypermutability (predisposition to mutation) that results from impaired DNA mismatch repair ...

Microsatellites are regions of repeated DNA that change in length (show instability) when mismatch repair is not working properly. MSI testing looks at the ...

Microsatellite instability (MSI), characterized by simple insertions or deletions of base pairs, is associated with mutations in genes concerned with ...